CBD For INFLAMMATION | How to use CBD for Inflammation

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CBD For INFLAMMATION | How to use CBD for Inflammation
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  • CBD for inflammation
  • Dosage
  • How to Use CBD
  • Best Time to take CBD
  • Side Effects of CBD
  • Pros & Cons of CBD on Inflammation

Inflammatory response acts as a barrier for the pathogenic microbes. Inflammation is a kind of swelling reaction. Inflammatory response serves as second line of defense of internal defense mechanism.

It is type of innate immunity i.e. inborn power to fight against diseases and this response also acts as a barrier for the foreign substance and pathogenic microbes. So, it is normal body’s response/ or act of defense.

How Inflammation Produced?

Antigen, when enters the body tissue produces toxic substance which kill the other cells. These broken cells release material which attracts the most cells which in turn releases histamine.

Histamine causes dilation of capillaries and small blood vessels surrounding the injury and increases permeability of capillary walls. As a result more blood flows to the area which makes it red and warm. Then the fluid oozes out which tries to nullify the response of antigen and causes swelling/inflammation.

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Causes of Inflammation:

Inflammation can be caused because of many reasons but most common reasons are auto immune disorders and allergies.

In auto immune disorders, due to unknown defects in one’s immune system body starts producing antibodies against the organs of one’s own body initiating the inflammatory response.

In allergic reactions, antigen: antibody reaction results in release of histamine which results in several other symptoms may include inflammation mostly in skin allergies. These can be the other causes of allergy:

  • AUTO IMMUNE DISORDERS
  • Arthritis
  • Hashimoto disease
  • Myasthenia gravis
  • Multiple sclerosis
  • Anemia
  • Chronic hepatitis
  • Type 1 diabetes and many more
  • METABOLIC SYNDROMES
  • ALLERGIES
  • Respiratory tract allergy like asthma
  • Skin allergy
  • Rhinitis- allergy of nasal lining
  • Anaphylaxis- blood allergy
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Types of Inflammation:

Two types of inflammation are there:

  1. ACUTE (SHORT-LIVED) INFLAMMATION
  2. CHRONIC (LONG-LASTING) INFLAMMATION

First talking about ACUTE inflammation, acute inflammation is short-lived, lasts for few minutes to few days depending upon the type of wound/ injury. Acute inflammation is the result of rapid flow of blood to the site of injured area and the plasma oozes out will help in healing the injury and also nullify the response of antigen/virus/bacteria. The onset of acute inflammation is rapid.

Signs by which one can recognize acute inflammation are:

REDNESS: redness occurs because of the increased blood flow.

HEAT: increased blood flow results in increasing the temperature and making the area warm.

SWELLING: edema occurs because of increased permeability of capillary valves,

PAIN: release of chemicals cause Swelling and tissue buildup begin to pressure against nerve cells. This pressure causes pain by sending pain signals to the brain.

LOSS OF FUNCTION: this is difficulty in proper functioning of the affected part.

CAUSES OF ACUTE INFLAMMATION

  • Tissue injury or pathogenic invaders.
  • Throat irritation from cough or cold.
  • ‘itis’ suffixed illness linked with inflammation. E.g. bronchitis and many more.
  • A wound or physical injury.
  • Exposure to dust or bee stings chemical.

When an acute inflammation which is not healing itself left untreated it may lead to chronic inflammation. For chronic inflammation other causes are also there including untreated acute inflammation. Next is all about chronic inflammation.

Chronic Onflammation

Secondly CHRONIC inflammation is the one lasting long, generally lasts from several months to years. Chronic inflammation is not easily recognizable as the acute one.

Unlike acute inflammation, it has negative impact on the body. In this inflammation, White blood cells follow the call of immune system but instead of resolving the problem, they unwittingly worsen it by rendering the membrane more brittle and prone to rupture. The onset of chronic inflammation is slow. It is the problematic one.

Chronic inflammation can affect your internal organs too. For e.g. inflammation of air tubes of lungs causing breath shortness, nephritis causing kidney failure or high blood pressure and heart inflammation. The reason behind how it happens is still unknown but researchers found several auto immune disorders, allergies and some other serious conditions linked to it. Possible outcomes linked to it are tissue breakdown, thickening, and bruising of connective tissues. More often this inflammation doesn’t show symptoms so to get it measured you need doctor’s consultancy always.

CAUSES OF CHRONIC INFLAMMATION

  • Autoimmune disorders: normal healthy tissues are affected by immune system by mistake. Combination of genetic and environmental factors is responsible for this. Different auto immune diseases can cause varied damage to varied body parts. Some of auto-immune disorders are:
  • Type 1 diabetes
  • Multiple sclerosis
  • Celiac disease
  • Myasthenia gravis
  • Lupus
  • Autoimmune arthritis
  • Myasthenia gravis
  • Inflammatory bowel disease
  • Psoriasis
  • Grave’s disease
  • Smoking: Cigarette smoking reduces the development of anti-inflammatory molecules and increases inflammation.
  • Low sex hormones: Inflammation is suppressed by sex hormones such as estrogen and testosterone. Reduced levels of these hormones, which are normal as people get older, raise the risk of inflammatory diseases.
  • Obesity: Pro-inflammatory chemicals are produced by fat tissue, especially visceral fat which causes inflammation.
  • Diet: Increased inflammation is linked to diets high in saturated fat, Trans fat, and refined sugar, particularly in people who are overweight.
  • Exposure to irritant: Chronic inflammation may result from long-term, low-level exposure to irritants such as chemicals.
  • Physical inactivity: When the muscles are in motion, a chemical reaction called anti-inflammatory occurs in the bloodstream. People who do not follow the minimum exercise guidelines are at risk for a variety of health problems, including long-term inflammation.
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Diagnosis of InfIammation:

Acute inflammation is symptomatic and more often there is no need to diagnose it. One can easily get to know about this inflammation by sensing it. To get confirm about it, doctors will prescribe you more than a single test to diagnose it. It includes physical examination and knowing the medical history of the patient so as to know the cause. Physical examination includes blood test and imaging.

BLOOD TESTS INCLUDE:

Presence of high level of these biomarkers in blood recognizes the inflammation.

  • (CRP) C-REACTIVE PROTEIN:

CRP is a protein that the liver produces in inflammatory process. People with chronic inflammation, inflammatory disorders, and acute inflammation have high CRP levels. A CRP level of 1 to 3 milligrams per liter of blood usually indicates a low but chronic level of inflammation.

  • (SPE) SERUM PROTEIN ELECTROPHORESIS:

It is the most reliable method of determining chronic inflammation. It detects any problems by measuring those proteins in the liquid portion of the blood. Inflammation may be caused by too much or too little of these proteins.

  • (ESR) ERTHYROCYTE SEDIMENTATION RATE:

ESR testing is commonly used to determine whether or not inflammation is present.

  • PLASMA VISCOSITY:

This test determines the thickness of a person’s blood. Edema or infection can cause plasma to thicken.

IMAGING INCLUDES:

  • NUCLEAR IMAGING
  • ULTERASOUND
  • Fluorodeoxyglucose POSITRON EMISSION TOMOGRAPHY
  • MRI

With these two categories of test, one can measure the inflammation.

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Treatment of Inflammation:

To get treated, first it is important to know treatment is for which inflammation? Acute or chronic? Treatment is given on the basis of age, considering overall health, severity of symptoms and already prescribed medications.

Inflammation treatment includes medications, surgery, home remedies, anti-inflammatory diet and usage of herbs.

MEDICATIONS

  • NONSTEROIDAL ANTI-INFLAMMATORY DRUGS (NSAID): The majority of these drugs, such as aspirin, ibuprofen, and naproxen, are legal and available. They help to relieve pain, swelling, fever, and other symptoms by inhibiting the enzyme. Some of them are not advisable for children so you should only use the one prescribed by the doctor.
  • CORTICOSTEROIDS: This is a form of steroid that is widely used to treat inflammation. Corticosteroids may be taken as pills or as injections. As these medications are known to cause adverse side effects, they should only used for brief periods of time.
  • ANTIMALARIAL MEDICATIONS: this includes hydroxychloroquine.
  • BIOLOGICAL DRUGS: biological drugs such as abatacept, certolizumab, etanercept, infliximab and humira are best recommended in chronic inflammation.
  • TOPICAL MEDICATION: these are having fewer side effects than an oral medication. Topical creams contain analgesics and steroids are advised for acute or chronic inflammation. If they contain an NSAID like diclofenac or ibuprofen, they can also help with long-term inflammation like in arthritis.
  • DIABETES MEDICATION
  • CHEMOTHERAPY MEDICATION such as methotrexate or cyclophosphamide.

SURGERY

Surgery is required when inflammation has severy damaged the joints. Surgeries are being done according to the severity of the condition. Several surgeries are:

  • Arthrodesis
  • Joint replacement
  • Osteotomy
  • Synovectomy
  • Arthroscopy

Home Remedies

 These remedies are also used in treating and preventing the inflammation. These include:

  • Keeping a check on your weight.
  • Limiting the alcohol intake.
  • Quitting smoking.
  • Taking proper sleep.
  • Managing stress.
  • Adding physical activity to your routine.
  • Adding some anti-inflammatory foods such as olive oil, nuts, fruits, tomatoes and green leafy vegetables to the diet.
  • Trying supplements having anti-inflammatory effects, such as green tea, omega-3 fatty acids and vitamins B6, C, D and E. Doctor’s advice should be taken before experimenting anything.

Herbs for Treatment (CBD for Treatment)

There are kind of herbs which can help in managing the inflammation.

  • TURMERIC: turmeric is having curcumin in it, which helps in giving benefits for arthritis and other inflammatory conditions.
  • GINGER: ginger is being used for constipation, colic and other gastrointestinal problems and also for rheumatoid arthritis pain from long time. Ginger can be used in its natural form or in the form of supplements too.
  • GRAPPLE PLANT: the herb of South Africa, has shown anti-inflammatory properties proved in a research.
  • CANNABIS: use of cannabidiol is promising treatment for several health issues. They also have anti-inflammatory properties. It is a natural remedy giving good results in comparison to the medications. Before using them one should know about their legality in their region.

Further we will know in detail about almost everything considering CBD FOR INFLAMMATION. Moving forward in this pattern, letting you know about CBD and all its properties in context of inflammation.

  1. HOW CBD HELP IN INFLAMMATION?
  2. HOW TO USE CBD FOR INFLAMMATION?
  3. BEST TIME TO TAKE CBD FOR INFLAMMATION?
  4. HOW MUCH DOSAGE SHOULD I TAKE?
  5. IS THERE ANY SIDE EFFECTS USING CBD FOR INFLAMMATION?
  6. TO REDUCE INFLAMMATION, SHOULD I TAKE CBD OR NOT?
  7. HOW LONG CBD WILL TAKE TO WORK ON INFLAMMATION?
  8. PROS AND CONS OF CBD FOR INFLAMMATION?

By now I think everyone knows something about CBD, but if still there are some misconceptions in your mind, we will help you in clearing that with the help of this article.

CBD is a cannabidiol obtained from hemp, and yes hemp and marijuana are totally different. So, CBD doesn’t make you high. There is legality of CBD products with less than 0.3% THC but still there are regions where it is not legal properly.

So, before using it make sure that it should be legal to take it in your area. Basically it is coming with results in treating varied range of issues including inflammation and getting popularity amongst the public because of its positive impact on health. Now let’s take your howzz and whyzz about CBD in the light of inflammation.

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How CBD help in Inflammation?

Inflammation as fully described above is of two type acute and chronic inflammation. So far it is effective in both inflammations. CBD is from one of the cannabinoid.

Endocannabinoid system (ENS) of the body reacts with the cannabinoids as ENS is having CB1 and CB2 receptors. CB1 mark their expression in CNS whereas CB2 receptors primarily give expression on immune cells. Pain, memory, mindset, metabolism, anxiety, sleep, appetite, immune function, and reproductive function are all regulated by the Human Endocannabinoid System (ECS).

Studies have shown the relation of cannabinoids to the ENS. Inflammation is an immune response and cannabinoids show immunosuppressive properties which is linked to suppressing the inflammation.

Cannabinoids prove themselves as anti-inflammatory agents by working in 4 ways.

Induction of apoptosis which is cell death is required for maintaining homeostasis. Canabinoids play protective role in autoimmune conditions by protecting apoptosis in cells of CNS.

Inhibition of cell proliferation, suppression of cytokine synthesis, and induction of T-regulatory cells are all ways in which they work.

Cannabinoids are also proven in giving effects in allergic asthma which is also an inflammatory disorder. Further more study is under process about the exact and true working of the cannabidiols for the sake of inflammation.

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How to use CBD for Inflammation?

CBD is available in varied range of products. Till date only single product i.e. in the form of oil is FDA approved. But any CBD product which is having less than 0.3% THC is legal for the purpose of medication.

CBD can be used in so much ways according to the need of the particular problem in a particular individual.

Several available forms which can be used for inflammation are:

  • In the form of oil or tinctures by taking them orally, sublingually i.e. under the tongue or adding in beverages like tea or coffee.
  • In the form of gummies.
  • In the form of capsules.
  • In the form of spray.
  • In the form of massage oil.
  • In the form of relief cream.

 All these products are having different dosages depending upon the form you are taking them. Most of the promising way till now is taking it orally, results coming for several health issues, using CBD in this way are best.  

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Best time to take CBD for inflammation?

Basically it depends upon the dosage and type of product one is taking and also on the reaction of the particular body towards the CBD.

Nothing is fixed for the best time. You can explore by experimenting which suits you/ best for you. For instance, some people experience swelling when they get up in the morning, there is feeling of no sensing in their body. For them it is ideal to take CBD at night/ before going to bed so that they can get the effect on morning which will eventually suppress that morning inflammation.

Best time depends on you and severity of the problem. You have leverage to choose which suits your body.

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How much Dosage should i take?

Dosage generally depends upon type of product, severity of the problem and tolerance level of body.

Moreover if you are new, just try it from a low level and wait for its effectiveness. Then according to your body’s call increase it, if needed. But never keep on exceeding; it may cause side effects rather than relieving the problem.

Approved dosage is for epilepsy only till now. Although CBD shown great tolerance level but still research is needed for setting proper dosage for particular problem.

Though the dosage is not approved by FDA.Still you can start with lower dosages and increase with time..  you can raise the dosage to 2-5 mg/pounds of body weight twice per day. It is based on person’s body weight and everyone is different according to body weight. So it is not possible to set a specific limit to everyone. So must consult to a doctor, especially if you are taking some other medications.

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Is there any side effect using CBD for inflammation?

Generally, for human consumption it is considered totally safe. But still, there are some mild side effects found in few consumers using it. They occur in high dose using patients, patients with low tolerance level, including age factor and taking it along with other medications.

Side effects include:

  • Dry mouth
  • Dizziness
  • Diarrhea
  • Appetite changes
  • Low b.p
  • Light headedness
  • Sign of liver damage in patients using ultra high doses

 So, it is suggested to get consultancy by your doctor.

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To reduce inflammation, should i take CBD or not?

Till now, if we see the research work , then there is a study on rats that reveals CBD can reduce inflammation in rats linked with osteoarthritis. A review also depicted its effectiveness in reducing inflammation.

One another review came in 2017 release that along with its anti- inflammatory properties, it may help in other conditions like multiple sclerosis, general pain, cardiovascular diseases and many more.

So, based on scientific reasons it can be suggested to use CBD in inflammation. One must consult your doctor, if you are suffering from multiple ailments.

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How Long CBD will take to work on Inflammation?

It totally depens upon how you are taking it and for which cause you’re comsuming it or are you taking it for one or more cause. So, the dosage totally depend according to the seriousness of the condition and according to that CBD wll work in your body.

Generally in case of inflammation, if applied as an ointment, it starts giving its effect within 15-45 minutes.

If taken as ingestible form, effects occur within 30 seconds to 15 minutes.

Also, if you are not getting the effect on time, try with other form or way of ingesting it, you can also wait and judge how your body react to it eventually you can add dose but again never go for high doses without recommendation.

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Pros and Cons

Evidently saying that using CBD have more advantages over disadvantages. Let’s have a look upon them and on this basis you can decide whether to give it a chance or not?

Pros
  • More positive outcomes
  • Scientifically validated
  • Legally accepted
  • Natural and promising relief
  • Natural healing properties
  • It’s possible that you’ll be able to get rid of your medication.
  • Single can aid in the treatment of a variety of conditions related to inflammation and other also such as anxiety, depression, epilepsy, allergic asthma, multiple sclerosis and many more.
  • Available in many form
  • Dosage and time can be personalized

Cons
  • Can give side effects if used along with other medications.
  • Availability of relevant research is limited.
  • Existence of goods that have not been licensed.
  • Some high-dose users have confirmed liver damage.
  • There are Mixed CBD with more THC impurities in the market.

We will be happy to hear your thoughts

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