CBD vs CBG | Difference & Similarities

CBD vs CBG  | Difference & Similarities

CBD has gain popularity amongst every industry since; because of its therapeutic benefits. There is a wave of CBD on the market after its legalization under the 2018 farm bills. CBD infused products are available in wide range means there are many options to choose from. There is still so many things are unrevealed about it. Researchers are trying to analyze as much as they can about CBD in all contexts.

It is now widely used, and most people are knowledgeable of its applications, availability, and usage. It has a magical effect on the endocannabinoid system, which makes it beneficial to human wellbeing.

Maybe you are curious what CBG stands for these days and why it is being compared to CBD?

Both CBD and CBG are the cannabinoids extracted from the cannabis plant and yes they posses several similarities as well as dissimilarities. Via this well-presented post, you can learn everything about them that makes them comparable and also about some of the key features of CBG.

From there abbreviations i.e. CBD and CBG that end letter make a lot difference. CBD stands for cannabidiol and CBG stands for cannabigerol. There is a lot to compare between them. They’re in high demand due to their non-psychoactive effects as well as the medicinal advantages they’ve been linked to.

Moving forward in the pattern:


Difference between CBD and CBG?

CBD do vary from CBG in many contexts like in terms of their terminology, chemical structure, extracting properties, legalized status, action on ECS, availability and current research status.


CBD stands for cannabidiol whereas CBG stands for cannabigerol.  Both differ in their chemical structutre. Both are type of cannabinoids but vary in their way of formation or extraction.

In the immature or young cannabis there is presence of CBG-A i.e. cannabigerolic acid which is acidic form of CBG and with the maturation of plant and in the presence of heat it changes into other cannabinoids except CBG. CBG-A is the precursor of all other cannabinoids, including CBD, which is why it is referred to as the “mother of cannabinoids.”

On the other hand, CBG is obtained by decarboxylation of CBG-A. As CBG-A is available only during younger stage of plant so, it is necessary to obtain or extract CBG before CBG-A get converted into other cannabinoids. This exercise of extracting at younger stage makes it difficult for manufacturer to get it in more quantity. Moreover CBG is present in minor quantities as compare to CBD. Researchers are developing some new strains which will be going to have more CBG in them. However, it is unclear when their studies will be successful.


On the basis of sayings, CBG interacts directly with endocannabinoid system. CBD, on the other hand, has been found to have an indirect relationship with the ECS. Direct actions can yield more results than indirect actions.

Still the research work upon their action is not 100% reliable as half of the scientists publish their study in relevant to the direct interaction of CBD with ECS whereas other supports indirect relationship. It will be clear only when major evidences support the specific study.


CBD being legal in many states without restrictions is gaining popularity. Its legalization is still in process in some states. It is no more in the list of scheduled 1 drug. CBD have gain FDA approval.

Moreover, WADA-WORLD ANTIDOPING AGENCY also exempted ban from it and now athletes are also allowed for its use. CBD is the only cannabinoid which is exempted by WADA till date. Researchers are working in knowing more medicinal benefits of CBD and how human bodies are responding to it.

In the other hand, no such legalization status for CBG is established at this time. It has not been licensed by any legal authority, nor has it been given proper permission to be used. As the rules are changing, when will be the appropriate research on its medicinal application become available, it is likely that it will achieve the legalized status that CBD currently enjoys.


Even after years of legalization, when it comes to making claims about CBD’s clear medicinal properties, further testing is needed. People are using it and sharing their personal experiences and positive impacts which is giving more lift to its use.

People are giving it a try as it is available in many forms. Many here mean in most of the eatables, beverages and also in the form of topical which providing pain relieving or some skin healing benefits. As it is present abundant in cannabis so it will help manufacturers to make more gain by extracting and selling it.

When talking about CBG, in terms of clinical research there are limited evidences of its medicinal properties. Since it is not considered authorized by officials, it is limited in its supply.

Because of fewer trials people are not showing much confidence to use it. Its minute presence is also a problem for manufacturers which makes its extraction an expensive process. As it processing is complex so it will be marketed more expensive than CBD.

It is a time to know how they are similar to each other;

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Similarties between CBD and CBG ?

In similar to CBD, CBG is also a cannabinoid, naturally present in cannabis. It acts on ECS of human body giving possible benefits in giving relief from several ailments. Both are having non-psychoactive effect which means they don’t give you high.

It is believed that they both suppress the psychotropic effect of THC, if someone unintentionally consumes cannabis or THC. They may also aid in getting relief from addiction related issues.

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Benefits of CBG on health


CBG can be considered as great pain reliever. In a paper study that tells about the promising pain analgesic property of CBG. Several diseases have link with pain like people suffering from migraine experiences pain of migraine, there can be arthritic pain or some other chronic pain.

Above mentioned study referenced that GABA uptake inhibitors are exhibited by CBG, which can result in muscle relaxation, stress relief, and a feeling of calm and peace in the body and mind and act as analgesics.


Glaucoma is a category of eye diseases in which the nerve linking the eye to the brain is affected, typically as a result of high eye pressure and this can lead to blindness. A Research concluded that for the treatment of glaucoma, CBG and associated cannabinoids may have therapeutic potential.

In this research, researchers gave CBG to glaucoma-affected cats and found a decrease in eye pressure and an improvement in aqueous humor outflow, a fluid created by the eye that regulates eye pressure and provides nutrients to the eye.


A paper published in 2020, evidences the anti-bacterial properties of CBG especially against MRSA, which is a bacterial strain resistant to methicilin antibiotic. This bacterium can cause threatening infection. Though this strain is resistant to traditional antibiotic but CBG is proven treatment against it concluded CBG an anti-bacterial agent.


A study by veldeolivas etal shows that CBG was discovered to function as a neuroprotectant, preventing damage to nerve cells in the brain. It also strengthens motor deficits and protects striatal neurons from the toxicity of 3-nitropropionic acid.

CBG reduced irregular gene expression related to brain degeneration, indicating that it is a neuroprotective drug. Mice affected from huntigton’s disease were treated with CBG resulting it as potent treatment of neurogenerative disease.


CBG was discovered to minimize inflammation and nitric oxide intake. When mice were given CBG, it also reduced the accumulation of reactive oxygen species (ROS) in the intestines and help in treating IBD in colons stated in research. IBD is inflammatory bowel disease. It can be also good for skin inflammations.


A research by pegano et al in 2015 concluded that CBG amongst the other cannabinoids is a promising treatment for bladder dysfunction.


A study came in 2014 revealed that CBG slowed tumor development in colon cancer affected rats and seemed to have some potential in blocking the receptors that cause cancer cell proliferation. Another study in 2016 added that CBG can serve as a direct inhibitor of tumor development as well as improve the efficacy of first-line therapies, as per preclinical reports. In another study in 2018 CBG along with other cannabinoids helps in treating breast cancer.

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What is CBG good for?

As above mentioned, animal health experiments have shown the efficacy of CBG. In a nutshell, CBG has the power to improve overall wellbeing. CBG fights inflammation, pain, and nausea, as well as slowing cancer cell proliferation.

It has shown that CBG-rich strains can be useful in the treatment of inflammatory bowel disease, cancer, glaucoma, neurogenerative diseases like huntigton’s disease, inflammotary diseases and also some bacterial diseases. In addition to this by acting on ECS it can also aid in immune related diseases and some other conditions like anxiety disorders, migraine and other chronic aches.

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Is CBG better than CBD?

After comparing it with CBD, there can be two ways which decides the benefits OF CBG over CBD. Like if we are going for its medicinal properties then yes it has wider area of application as compare to CBD on the basis of current researches available yet.

Since it interacts more strongly with ECS than CBD, it can provide more promising benefits. Furthermore, it has been shown to be a more effective pain reliever than CBD.

If we go for its research side and legalizing issue, then yes it lacks behind CBD here. There are currently no known side effects associated with CBG due to lack of clinical trials. CBG is not yet authorized by authority which is also a demerit of it.

No doubt it possesses more therapeutic effects than CBD but it is also true that its side effects have not been known yet. There is lot of scope in research of CBG. So we have to wait for its human trials to say whether it is better than CBD or not.

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